If the CDC states frozen sections should not be performed on known CJD
specimens I think that in itself is a valid argument.    Afterall, 24 hours
is not long to wait for 'permanent' sections to be obtained.
And I doubt waiting 24 hours  changes the protocol for treatment outlook for
these patients.
> -----Original Message-----
> From:	Gayle Callis [SMTP:uvsgc@msu.oscs.montana.edu]
> Sent:	Monday, March 06, 2000 03:59 AM
> To:	histonet@pathology.swmed.edu
> Subject:	CJD question, frozen sections
> 
> I think you have effectively put yourself out of the frozen section
> business in fact, histopathology laboratory business. 
> 
> I agree with another comment, risks are still there even with paraffin.
> How about those bloody tissues not completely fixed, infectious agents are
> still viable (other than CJD) which 'lives' on to 'bug' you forever.  
> 
> There are ways to safely work with frozens, hence all the discussion a
> couple of weeks ago on ways to disinfect a cryostat.   I suggest you
> rethink your policy.
> 
> 
> 
>  
> 
> Gayle Callis
> Veterinary Molecular Biology
> Montana State University
> Bozeman MT 59717-3610
> 406 994-4705
> 406 994-4303