RE: uranium in histologic procedures
|From:||"Weems, Joyce" <JWEEMS@sjha.org>|
We purchase the 1% from PolyScientific. It's warnings would scare the pants
off ya! Nothing about being depleted.
Saint Joseph's Hospital of Atlanta
From: RSRICHMOND@aol.com [SMTP:RSRICHMOND@aol.com]
Sent: Friday, February 09, 2001 12:20 PM
To: HistoNet@pathology.swmed.edu; PATHO-L@listserv.cc.emory.edu;
Subject: uranium in histologic procedures
Uranium nitrate (uranyl nitrate) is used in a few histologic stains,
particular silver impregnation stains, including a recently
for Helicobacter. Questions are often raised about its radiotoxicity
chemical toxicity. A recent editorial in The Lancet is informative.
Toxicity of depleted uranium - by N.D. Priest (School of Health,
and Environmental Sciences, Middlesex University, London N11 2NQ, UK
email@example.com) The Lancet 27 Jan 2001; 357: 244-6. (I suppose
the Web, but I've got a paper copy.)
Priest describes depleted uranium as uranium from which 70-80% of
radioactive U-235 and U-234 have been removed. Depleted uranium has
commercial use in several settings, including X-ray shielding in
but it has recently gained notoriety because of its use in
munitions in the former Yugoslavia (and in fact earlier, in the Gulf
Of histologic interest is the statement that "Depleted uranium has
natural isotopic composition as a less radioactive substitute for
some uses -
e.g., laboratory chemicals." Is this substitution stated on labels?
have a recent label to check. - The substitution is not sufficient
computations at the level of precision needed in histologic work.
Priest's review suggests that the need for chemical or radiologic
with handling uranyl salts is not very great from a practical
though what keeps the Herrn Inschpektors happy is another question.
(Parenthetically, some bottles of lithium carbonate note that the
been depleted of lithium 6 - used in making tritium for hydrogen
bombs - and
this substitution might actually be of soposition.)
I've cross posted this note to the pathologists' PATHO-L list and to
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