Re: Cytoplamic staining in P53 and Ki-67
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| From: | RUSS ALLISON <Allison@cardiff.ac.uk> |
| To: | "histonet@Pathology.swmed.edu" <histonet@pathology.swmed.edu>, Dave Tacha <dtacha@ncal.verio.com> |
| Reply-To: | |
| Date: | Mon, 06 Sep 1999 17:30:12 +0000 (GMT0BST) |
| Content-Type: | text/plain; charset=US-ASCII |
The specificity and sensitivity of cell proliferation markers can be
affected by fixation (and processing - probable).
See :
Allison & Best. p53, PCNA and Ki67 expression in oral squamous cell
carcinomas: the vagaries of fixation and microwave enhancement of
immunocytochemistry. Oral Pathol & Med. 1998;27:434-440
Russ Allison, Wales
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