Re: Cytoplamic staining in P53 and Ki-67

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From:Sarah Christo <>,,
Date:Mon, 06 Sep 1999 13:21:05 -0500
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Dear Russ,
   Hey, guess why the Histonet is so slow today, it's a National Holiday today: Labor Day.  I think I am the only one working!  In the infinite wisdom of Texas A&M University, we have Martin Luther King Jr. day off but not Labor Day or Memorial Day.  Just thought you might want to know since I always enjoy hearing about the Holiday's ya'll have over there.  Should be more activity tomorrow.   -Sarah

Sarah Christo, HT (ASCP)
Texas A&M University
College of Veterinary Medicine
Dept. of Vet. Anatomy & Public Health
College Station, TX  77868-4458

>>> RUSS ALLISON <> 09/06 12:30 PM >>>
The specificity and sensitivity of cell proliferation markers can be 
affected by fixation (and processing - probable).
See :
Allison & Best.  p53, PCNA and Ki67  expression in oral squamous cell 
carcinomas: the vagaries of fixation and microwave enhancement of 
immunocytochemistry. Oral Pathol & Med. 1998;27:434-440
Russ Allison, Wales

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