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On Sat, 03 Oct 1998 11:34:41 -0700, Heike Grabsch wrote:

>in case you are suspecting M.Wilson, which means excessive copper storage
>for example in the liver, what sort of staining do you use and what sort
>of positive control?
>And is any body able to send us a positive control tissue block?

There's is a recent article in Histopathology 1998,33,28-33 by Pilloni, L
et al about the value of different
cooper stains in the diagnosis of WD. In short, the results are
disappointing, the common Rhodamin stain fails
quite often, best method is TIMM's which I haven't tried til now.

BTW: as the journal with the original Timm's procedure is not available
(published in Histochemie 1961) in
Vienna, could anybody send information about it?


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