Re: Formaldehyde substitutes

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From:Geoff McAuliffe <mcauliff@UMDNJ.EDU> (by way of histonet)
To:histonet <>
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P. Emry wrote:
> Hey Gang,
> I got the boss to consider formaldehyde substitutes.  She wants to see a
>"PAPER" on comparisons.  I am getting literature from vendors, but I would
>like to get some independent information..a journal is what she has in
>mind. Could you(s) give me a reference or send me a paper that would
> help me with the boss?  She's great, but traditions are hard to abandon.
> I and my pickled lungs (eyes, sinuses et.) thank you.
> Trisha Emry
> Orthodontics Research Lab
> University of Washington
> Box 357446
> Seattle, WA  98195
> (206) 685-8163 fax

	See "Commercial Formalin Substitutes for Histopathology" by Prento and
Lyon, 1997, Biotechnic and Histochemistry (formerly Stain Technology)
72:273-282. Boils down to "We conclude that none of the proposed
commercial substitutes for buffered formalin are adequate for critical
histology or histopathology".

Geoff McAuliffe, Ph.D.
Neuroscience and Cell Biology
Robert Wood Johnson Medical School
675 Hoes Lane  Piscataway, NJ 08854
voice: (732)-235-4583; fax -4029   e-mail:

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