TTF is an abbreviation for thyroid transcription factor. TTF1 is positive
on epithelial cells of thyroid and lung, so normal lung or thyroid would
make a good control to work out the titer & pretreatments. Once you have
these conditions worked out, you can work it up on a variety of tumors and
check your sensitivity and specificity. TTF1 is positive on primary lung &
thyroid adenocarcinomas, and small cell carcinomas of any origin.
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