LN2 snap freezing vs -80?

From:jason madore

Has anyone had any experience with LN2 snap freezing vs. slow freezing at 
-80. I was wondering if there is a difference in ease of cryosectioning, RNA 
stability, morphology, etc... The samples are all embedded in OCT first. 
Does the formation of ice crystals by slow freezing cause tissue to tear 
when crysectioning?
thanks.
jason.

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