----- Original Message -----
From: Jill and Earl Farley <celebrit@mail.clis.com>
To: Teri Johnson <terij@prlnet.com>
Sent: Tuesday, June 20, 2000 6:51 PM
Subject: Re: H.O.D (hereditary osteo-dystrophy)


Well- here is some info-
The WCA magazine runs an ad about vaccines-
>
> "Immune Mediated Problems and Vaccination"
>  A small percentage of Weimaraner puppies manifest an autoimmune reaction
> following vaccination with combination MLV (modified live virus) vaccines.
> When the immune system of susceptible individuals is challenged by
multiple
> antigens it becomes hyperreactive and responds in the same way it would to
> fight an infection; fever, elevated WBC and inflammatory reaction of
tissues
> and joints.
> Although many puppies can be vaccinated with the combination MLV vaccines,
> there is no way at the present time to determine which pups are going to
> adversely react. Therefore, the  Board of Directors of the Weimaraner Club
> of America recommends that when vaccinating puppies the Distemper and
Parvo
> vaccines be administered separately, a two week interval between each
> vaccine. Any other vaccines should be administered separately as well.
> While this vaccine protocol helps in preventing autoimmune reactions, it
> does not prevent it in all susceptible individuals.
>
> That being said, I never follow the advice. Tammy does the same as I with
> the theory of- we want to know which pups have an autoimmune problem so we
> don't repeat the breeding. To date we have never had a problem. We use MLV
> combo at 6, 9, 12, 15, and 18 weeks and never had more than a little
> lethargy for a day or a tender knot at vaccine site.
> A client did have a weim pup who had all the classic symptoms
> post-vaccination; swollen joints, fever, listless, etc.  Dr. Bird never
> acknowledged what I told him, but treatment would have been the same. I'll
> let you know if he has a reaction when he has his annual booster.
> I think the WCA note saying that there is no present test to see if pup is
a
> carrier answers one of her questions. The staining material info she could
> probably get from the lab at any vet school, including calling her own
vet's
> lab and speaking with the techs there. (It would be the first place I
would
> call.)
> I am putting in a link to  the WCA homepage for her if it helps-  they
have
> a health issue section.
>
> http://www.geocities.com/Heartland/Prairie/2747/
>
> This is an article on HOD:
>  http://www.geocities.com/Heartland/Valley/5340/index.html
>
>
> Tarheel Weimaraner Club Homepage
>  http://www.geocities.com/Heartland/Valley/5340/index.html
>
> I hope she finds something of use to her; we never see HOD (but bad bites,
> low tail sets, etc.!)so hopefully someone else can give her info.
> Hope this helps!
> Jill
>
>
> ----- Original Message -----
> From: Teri Johnson <terij@prlnet.com>
> To: <celebrit@mail.clis.com>
> Sent: Tuesday, June 20, 2000 1:39 PM
> Subject: Fw: H.O.D (hereditary osteo-dystrophy)
>
>
> >
> > I'm forwarding you this letter that was posted on our listserver.  Do
you
> > have any answers for her?
> >
> > -Teri
> > ----- Original Message -----
> > From: Cathie Crukley <Cathie.Crukley@sjhc.london.on.ca>
> > To: <histonet@pathology.swmed.edu>
> > Sent: Tuesday, June 20, 2000 10:05 AM
> > Subject: H.O.D (hereditary osteo-dystrophy)
> >
> >
> >
> > I am posting for information again from the veterinary medicine people
on
> > the list.
> >
> > Some time ago I was asking for information on the relationship between
> > combined vaccines and H.O.D. before acquiring my Weimaraner puppy.  My
> puppy
> > is five months old now, I did vaccinate her separately and she has been
> > fine, two of her littermates have come down with H.O.D. and one of them
> has
> > died, both were male.
> >
> > Can anyone tell me if there is a test available to determine if a dog is
a
> > carrier and what type of sample would be required?  Also, are probes
> > available to stain the joint material for the presence of distemper and
> > parvo?
> >
> > I would appreciate references if any are known.
> >
> > Thanks,
> >
> > Cathie Crukley, MLT
> > Immunopathology Lab, SJHC
> > London, Ont.
> >
> >
> >
> >
>
>