Re: stain for alzheimers
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From: | "J. A. Kiernan" <jkiernan@julian.uwo.ca> |
To: | |
Reply-To: | |
Date: | Tue, 21 Sep 1999 13:22:12 -0400 (EDT) |
Content-Type: | TEXT/PLAIN; charset=US-ASCII |
> i am looking for a stain to determine alzheimers disease. would appreciate
> any suggestions from anybody out there.
> thanks so much, anita
One of Ferenc Gallyas's silver methods is currently much
favoured by neuropathologists because of its high sensitivity
and clean background.
Gallyas F & Wolf JR 1986. Metal-catalyzed oxidation renders
silver intensification selective. J Histochem Cytochem
34: 1667-1672.
There is a modification for large (whole human brain sections):
Braak H & Braak E 1991. Demonstration of amyloid deposits and
neurofibrillary changes in whole brain sections. Brain
Pathol. 1: 213-216.
John A. Kiernan,
Department of Anatomy & Cell Biology,
The University of Western Ontario,
LONDON, Canada N6A 5C1
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