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Hi Rick,<br>
<br>
I assume you want to replace this with a histology/pathology
oriented system. I am further going to guess that DNA ploidy quantitation
by Feulgen reagent and semi-quantitative single color
immunohistochemistry (HRP/DAB staining) are among the applications. The
two companies I've been most impressed by in these areas are:<br>
<br>
ImagePath Systems, Inc.
<a href="http://www.imagepath.com/" eudora="autourl">http://www.imagepath.com/</a><br>
<br>
and<br>
<br>
Bacus Laboratories Inc
<a href="http://www.mcs.net/~bacuslab/" eudora="autourl">http://www.mcs.net/~bacuslab/</a>
<br>
<br>
I was very impressed with Al Floyd of ImagePath when I met him at the Biological Stain Commission meeting in Long Beach this summer ( <a href="http://www.urmc.rochester.edu/SMD/Path/BSC/nextmeet.html" eudora="autourl"><font color="#0000FF"><u>http://www.urmc.rochester.edu/SMD/Path/BSC/nextmeet.html</a></font></u> ). Bacus was the brains behind the late (and largely unlamented) CAS 200. Bacus seems mostly interested in telepathology nowadays.<br>
<br>
<br>
If you just need a simple image analyzer, Image Pro+ (<a href="http://www.mediacy.com/" eudora="autourl">www.mediacy.com</a>) or IPLab from Scanalytics (<a href="http://www.scanalytics.com/" eudora="autourl">www.scanalytics.com</a>) are pretty good and support lots of cameras. The former is the better Windows product.<br>
<br>
<br>
If this is for documentation only (not for clinical quantitation), you may want to simply get a good camera that can capture images through Adobe Photoshop (typically through a "TWAIN" driver). The digital/color SPOT-2 camera comes to mind ( <a href="http://www.diaginc.com/spot.htm" eudora="autourl">http://www.diaginc.com/spot.htm</a> ) and can be used with Image Pro+ or IPLab as well.<br>
<br>
My three rules of thumb are:<br>
<br>
1. Buy the stuff that nails your main application.<br>
2. An excellent camera is an excellent investment (if it helps nail your application).<br>
3. Get a software package that is easy to learn and use, and outputs the data you need, quickly.<br>
<br>
<br>
By the way, in the unlikely event that multicolor FISH is your major need, contact me directly.<br>
<br>
<br>
>Date: 8 Sep 1999 12:45:46 -0500 <br>
>From: maliniakrm@worldnet.att.net <br>
>Subject: Image Analysis<br>
>We are currently interested in replacing our 'outdated' SAMBA Image <br>
>Analyzer. Any recommendations!<br>
>Rick Maliniak<br>
<br>
<br>
<br>
<br>
<br>
<br>
George McNamara, Ph.D.<br>
Applied Spectral Imaging, Inc.<br>
2120 Las Palmas Drive, Suite D<br>
Carlsbad, CA 92009<br>
voice<x-tab> </x-tab>760-929-2840 ext 17<br>
fax<x-tab> </x-tab>760-929-2842<br>
<font color="#0000FF"><u>Electronic Mail</font></u> <font color="#0000FF"><u>Geomcnamara@earthlink.net</font></u> <br>
or <font color="#0000FF"><u>George.McNamara@spectral-imaging.com</font></u><b> <br>
</b><font color="#0000FF"><u>Company Web Site</font></u> <a href="http://www.spectral-imaging.com/" eudora="autourl"><font color="#0000FF"><u>http://www.spectral-imaging.com<br>
</a>Personal Web Page</font></u> <a href="http://home.earthlink.net/~geomcnamara/Index.html" eudora="autourl"><font color="#0000FF"><u>http://home.earthlink.net/~geomcnamara/Index.html<br>
</a></font></u>Imaging Applications for Molecular Cytogenetics, Pathology & More: <br>
<font color="#0000FF">S</font><font color="#FF00FF">K</font><font color="#008080">Y</font> <font color="#FF00FF">- </font><font color="#000080">S</font><font color="#FF0000">p</font><font color="#808000">e</font><font color="#800080">c</font><font color="#008000">t</font><font color="#0000FF">r</font><font color="#FF00FF">a</font><font color="#0000FF">l</font> <font color="#000080">K</font><font color="#808000">a</font><font color="#FF0000">r</font><font color="#800000">y</font><font color="#0000FF">o</font><font color="#008080">t</font><font color="#0000FF">y</font><font color="#FF0000">p</font><font color="#0000FF">i</font><font color="#FF00FF">n</font>g <br>
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