RE: [Histonet] FLI-1

From:"Houston, Ronnie"


Fli -1 is a nuclear endothelial marker, and appears to be involved in proliferation and tumorgeneisis

You can get the polyclonal antibody from Santa Cruz Biotechnology, cat  sc356 (the UK # is 800 4573 8000). We have used it for quite some time now, and the pathologists think it is great.
You may want to look at the following article:

Expression of Fli-1, a nuclear transcription factor, distinguishes vascular neoplasms from potential mimics.
Folpe AL, Chand EM, Goldblum JR, Weiss SW,
Am J Surg Pathol 2001; 25(8): 1061-1066

Ronnie Houston
Regional Histology Operations Manager
Bon Secours HealthPartners Laboratories
5801 Bremo Road
Richmond, VA 23226
(804) 287 7972

-----Original Message-----
From: Fearn Tony []
Sent: Thursday, September 25, 2003 8:15 AM
To: ''
Subject: [Histonet] FLI-1

> One of our pathologists has just returned from a conference in Milan and
> is asking if we can get FLI-1, as an endothelial marker, that is meant to
> be better than CD34. I've looked in the DakoCytomation and Novocastra
> catalogues but there is no mention of it. Does anyone know where I can get
> it, and is it worth buying?
> Anthony J Fearn
> Chief Biomedical Scientist
> Histopathology

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