Amyloid Red (Direct red 72)
Just come in the mail from Anatech is Vol 4., No. 2 of The Innovator, Autumn
2001.
They describe a product I'd certainly want to look at if I were trying to
stain amyloid. What they have named "Amyloid Red" they describe as a ureylene
(rather than benzidine) based dye, which according to their MSDS is Direct
red 72 which is C.I. 29200 and CAS#10114-26-6. It is supposed to replace
Congo red in amyloid staining. It colors amyloid, with the same birefringence
(polarization) properties as Congo red.
Obsolete as a textile dye for many years, benzidine-based Congo red is now
listed by OSHA as a carcinogen, and is likely to go out of manufacture.
Anatech, please put this very informative article on your Web site where
everybody can read it!
http://www.anatechltdusa.com/
http://my.net-link.net/~anatech/www/anatech/MSDSfolder/AmyloidRedMSDS.html
The same issue of The Innovator contains updates on Anatech's manufacture of
Alcian blue, and on their formulation of brazilin (similar to hematoxylin,
but much redder) as a nuclear stain to replace Nuclear Fast Red.
Bob Richmond
Samurai Pathologist
Knoxville TN
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