Dorothy:
At the end you are going to use tissues from your laboratory to do the tests, and you do not know how other labs processed their tissues. Although it is not absolutely clear how the processing steps (other than fixation) can affect the reactivity of a tissue, it is always better not to introduce more variables than necessary, so I would use tissues from my own laboratory.
René J.

--- On Mon, 10/6/08, Webb, Dorothy L  wrote:

From: Webb, Dorothy L 
Subject: [Histonet] validation
To: histonet@lists.utsouthwestern.edu
Date: Monday, October 6, 2008, 10:16 AM

Is it better to use a lab's own tissue for validation in a microarray
for Ihc purposes or would it be passable to use TMA's from another
source??  Thanks for your opinions!!

Dorothy Webb, HT (ASCP)
Histology Technical Supervisor 
Regions Hospital, Pathology Department 
640 Jackson Street, Saint Paul, MN 55101-2595 
Phone: 651-254-2962
Fax: 651-254-2741 
Regions Hospital is part of the HealthPartners family of care
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