That is a known disadvantage of some xylene substitutes.
  René J.

buck45@optonline.net wrote:
  Hi - 
I was wondering if anyone who uses xylene substitutes have had problems with the eosin bleeding out of the tissue. I don't know if it is the type and brand of eosin or something else. I have never used a substitute before and I find that the stainer needs to be changed much more that with regular xylene. I seem to get a lot of water on the slides unless I change it every other day.
Gail
Paramus, NJ
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