I just did a search of the histonet archives yesterday on this very
subject. Go to www.histosearch.com/histonet and type in matrigel in the
search box. Others have had difficulty with cryosectioning it in the
past as well.
Apparently it paraffin processes and sections just fine. You might see
if this is an option instead.
Teri Johnson, HT(ASCP)QIHC
Managing Director Histology Facility
Stowers Institute for Medical Research
1000 E. 50th St.
Kansas City, MO 64110
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