Re: [Histonet] Vison BioSystems - Peloris

From:"Anthony Reilly"

Hi Richard

My peloris was part of the very first relase of the instrument.  As a
result there were some initial minor problems which have since been
rectified.  As I said these problems were minor and never in any way
affected the processing of our tissue.

It now runs very well and has had a positive impact on our laboratory.
The instrument has a very powerful mixing ability which not only
improves penetration but guarantees even heating on the steps where heat
is utilised giving shorter processing times even for fatty tissue. This
is aided by using one of their range of specimen baskets which separates
each cassette individually allowing better flow of solution to each

Our laboratory services both heart and lung transplant units requiring
us to run numeroous short cycles throughout the day.  The improved
processing combined with a rapid clean cycle means that the one dual
retort peloris can do the work of 3-4 of our prevoius instruments.

Examples of our improved times include:

Fatty tissue 18h to 14h
Routine 12h to 9h
Small Biopsy 2h to 1 h

This has also had an impact on IHC as the small biopsies that are
required urgently can be given an extra 1h in formalin and still be
completed in the same time as the previous protocol.  With the faster
processing some tissues such as lletz biopsies need to be processed on
shorter cycles to avoid hardening of the tissue.  According to the
manufacturer these times can be reduced further by substituting xylene
with isopropanol but I have not tried that so cannot comment.


Tony Reilly
Chief Scientist
Anatomical Pathology
QHPS-Prince Charles Hospital
Rode Rd Chermside Q 4032
Ph: 07 3139 4543
Fax: 07 3193 4546

>>> "Richard Cartun"  10/15/06 11:46 pm >>>
Anyone out there using Vison BioSystems' "Peloris" for tissue
processing?  If so, what has been your experience?  Thank you.


Richard W. Cartun, Ph.D.
Director, Immunopathology & Histology
Assistant Director, Anatomic Pathology
Hartford Hospital
80 Seymour Street
Hartford, CT  06102
(860) 545-1596
(860) 545-0174 Fax


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