Re: [Histonet] STP420 from Richard Allan. .

From:"Wesley Simms, MD"

Rene,
Yes indeed, I was told last week by the nice pathologist from Miami (whose name eludes me at the moment) who Sakura brought in to teach us to use the new grossing tools that raw tissue, even if sliced at 1.5mm thick, could not be put on the machine.  He quoted the 4 hour figure for breast tissue in particular.  When I saw the graph of Miami's FTE staffing for HT's and pathologists by time of day (before and after Xpress), I was also puzzled as to how this would translate into any tangible benefit, either cost-wise or by improved patient care.  The only result I could see was that everyone's day is going to start later and be strung out over a longer period of time.  My wife, who is an attorney, summed it up best:"At least with the old processor, something was doing work overnight and being productive.  Now, with the new one, nothing is."
Wesley Simms
  ----- Original Message ----- 
  From: Rene J Buesa 
  To: Wesley Simms, MD ; histonet@lists.utsouthwestern.edu 
  Sent: Tuesday, October 10, 2006 10:32 AM
  Subject: Re: [Histonet] STP420 from Richard Allan. .


  Dr. Simms:
  According with Morales et al. ("inventors") you can process tissue in the Xpress that has not been previously fixed, now it turns out that you cannot?

  That is another drawback yet, because it is also not true that you will be able to process 120 cassettes in 1 hour; their mathematics do not add up.
  The protocol (2 stations with MW assisted protocol) + 2 "conventional" stations (just convection heating + vacuum) takes 60 minutes to complete (15 min each).
  The only real advantage seems to be that you can introduce 30 cassettes every 15 minutes in the first station.
  This means that you will have 30 cassettes processed in 1 hour, the following 30 (to a total of 60) the next 15 minutes (=75 minutes) and so on until you get to the 120 cassettes after 105 minutes.

  And all of this has nothing to do, has not impacted at all, on the time required for manual work (grossing/cassetting, embedding, trimming and sectioning the blocks) that will amount to a total of 149 minuttes per every 30 cassettes, even allowing that there will be automated instruments to write cassetes, etch slides, routine stain and coverslip.

  The "famous" 120 cassettes / hour turn out to be a total of 105 min. processing + 160 minutes of automated ancillary tasks +  596 minutes of manual work, for a grand total of 861 min =14.4 h / 120 cassettes = 2.4 FTE with 75% time utilization on 8h shifts!

  I could also buy a good house with $250,000!
  Just a few "numbers" about the Xpress (no reagents cost included of course!)
  René J.

  "Wesley Simms, MD"  wrote:
    By "real" time, I refer to the fact that you can't load fresh tissue on the 
    Xpress...even if it sliced at the requisite 1.5mm, several hours of fixation 
    is required (4 hours for breast). Ergo, the "real" processing time for 
    breast on the Xpress is five hours. In terms of cost, I have found a nice 
    lakefront house in the Florida panhandle and a new boat that I can buy for 
    the same price as an Xpress ($250,000). My informed sources also tell me to 
    expect quadrupled reagent costs with the Xpress, so yes, I think your use of 
    the term "stratosphere" is appropriate. I don't know the price of the 
    STP240, but I cannot imagine that it is as expensive, given that it is, 
    essentially, a turbocharged conventional processor. If the STP240's total 
    processing time is in the 5 hour ballpark, I would certainly be interested 
    in looking at one.
    Wesley W. Simms
    ----- Original Message ----- 
    From: "Jasper, Thomas G." 
    To: "Wesley Simms, MD" 
    Cc: 
    Sent: Monday, October 09, 2006 3:56 PM
    Subject: RE: [Histonet] STP420 from Richard Allan. .


    Wesley,
    Could you clarify a bit? What do you mean by "real" time? And you are 
    certain that the two are not comparable in terms of cost. Does this mean 
    that the Tissue Tek Express is priced in the "stratosphere" or does it mean 
    that the price is justifiable due to "real" time savings? Or is the price 
    of the STP420 excessive because it doesn't do what the Tissue Tek Express 
    does? Or is it a great deal because it does process quickly at a 
    substantially lesser cost?
    Your statement begs for more information, because I can't tell where you 
    stand on the issue.
    Thanks,

    Thomas Jasper
    AP Supervisor
    SMDC
    Duluth, MN

    -----Original Message-----
    From: histonet-bounces@lists.utsouthwestern.edu
    [mailto:histonet-bounces@lists.utsouthwestern.edu]On Behalf Of Wesley
    Simms, MD
    Sent: Monday, October 09, 2006 2:21 PM
    To: histonet@lists.utsouthwestern.edu
    Subject: Re: [Histonet] STP420 from Richard Allan. .


    How do the "real" processing times on the STP 420 compare with the Tissue
    Tek Xpress? I feel certain that the two are not comparable in terms of
    cost.
    Wesley W. Simms
    ----- Original Message ----- 
    From: "Tarango, Mark" 
    To: "Henry, Charlene" ;

    Sent: Monday, October 09, 2006 1:56 PM
    Subject: RE: [Histonet] STP420 from Richard Allan. .




    Works great. I've never had a problem with it. I like that it is two
    tissue processors in one (has two chambers that can be ran at the same
    time). I've recently heard there are about 10 out there already.
    Hopefully someone else will make a comment about it.



    Mark Adam Tarango HT(ASCP)
    Histology/Immunohistochemistry Supervisor
    Nevada Cancer Institute
    One Breakthrough Way
    Las Vegas, NV 89135
    mtarango@nvcancer.org
    Direct Line (702) 822-5112
    Fax (702) 939-7663



    -----Original Message-----
    From: Henry, Charlene [mailto:Charlene.Henry@STJUDE.ORG]
    Sent: Monday, October 09, 2006 6:39 AM
    To: Tarango, Mark
    Subject: RE: [Histonet] STP420 from Richard Allan. .

    How is the instrument performing for you?


    Charlene Henry HT (ASCP), QIHC
    Histology/Immunohistochemistry Section Head
    Department of Pathology
    St. Jude Children's Research Hospital
    901-495-3191
    fax 901-495-3100

    -----Original Message-----
    From: histonet-bounces@lists.utsouthwestern.edu
    [mailto:histonet-bounces@lists.utsouthwestern.edu] On Behalf Of Tarango,
    Mark
    Sent: Friday, October 06, 2006 2:04 PM
    To: Angela Bitting; histonet@lists.utsouthwestern.edu
    Subject: RE: [Histonet] STP420 from Richard Allan. .



    I have the STP420. The last time I heard I was the only one in the US
    who has one.


    Mark Adam Tarango HT(ASCP)
    Histology/Immunohistochemistry Supervisor Nevada Cancer Institute One
    Breakthrough Way Las Vegas, NV 89135 mtarango@nvcancer.org Direct Line
    (702) 822-5112 Fax (702) 939-7663




    -----Original Message-----
    From: histonet-bounces@lists.utsouthwestern.edu
    [mailto:histonet-bounces@lists.utsouthwestern.edu] On Behalf Of Angela
    Bitting
    Sent: Friday, October 06, 2006 11:54 AM
    To: histonet@lists.utsouthwestern.edu
    Subject: [Histonet] STP420 from Richard Allan

    Has anyone had experience with this rapid tissue processor?( No vendors
    please)


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