[Histonet] how to count nodules in a xenograft model
I am posting this on behalf of a friend. I know very little about
xenograft models and I thought someone on this list may have more
Essentially, she is injecting MDA-MB-231 cells i.v. in mouse and
studying metastasis. She wants to get a count of the nodules that
form in the lung. Does anyone have a good protocol for doing this.
She has little histology skills, so most likely she will send the
tissue to a lab to process. What is the safest way to collect the
tissue, how should it be processed, and how does one get a good idea
of the number of nodules formed?
Any help would be appreciated.
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