RE: [Histonet] IHC withquantum dots

From:Gayle Callis

Patsy and everyone,

QDots are the hot new thing on the market, nanocrystals that can be 
conjugated to Strepavidin, antibodies and mnay othre things, i.e. proteins. 
They vary in size and are highly fluorescent, and are very pricey.   The 
different nanocrystal sizes determine the final color that is emitted after 
excitation which is extremely bright and doesn't photobleach, a wonderful 
thing for those of us who work with confocals and fluorescence microscopes.

You can learn more about them by going to  The website has 
excellent explanations on QDots, a good place to learn about 
adsorption/emission, etc basic explanations on fluorescence.   Science 
magazine has many publications in the past few years explaining their 
structure and applications in animals/tissue research, including breast 
cancer research.

Gayle Callis
Research Histopathology Supervisor
Veterinary Molecular Biology
Montana State University - Bozeman
PO Box 173610
Bozeman MT 59717-3610
406 994-6367 (lab with voice mail)
406 994-4303 (FAX)

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