RE: [Histonet] EDTA

From:"Barry R Rittman"

Margaret
EDTA itself is only slightly soluble in water.
As you start to make the solution more alkaline e.g. by slowly adding
sodium hydroxide solution, it will start to dissolve. Then adjust pH to
what you finally want.
An easier approach is to start with disodium EDTA which is very soluble
in water and then adjust the pH.
Barry

Barry. R. Rittman
6516 MD Anderson Blvd.
Houston, TX. 77030

713-500-4134	telephone
713-500-4500	fax

-----Original Message-----
From: Wilhelms, Margaret B
[mailto:margaret_b_wilhelms@groton.pfizer.com] 
Sent: Monday, October 20, 2003 7:59 AM
To: 'histonet@lists.utsouthwestern.edu'
Subject: [Histonet] EDTA

I've seen lots of posts in the archives about EDTA and formulas.  But I
have
a question:  Has anyone had any trouble getting EDTA powder to dissolve
in
distilled water?

Meg



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