Re: underprocessed tissue

From:Histo-Scientific Research Laboratories

Dear Bob,

Underprocessed tissue will either puff out of your block upon soaking on ice
or it will be sunken into the block.  It may be mushy to the touch and as
you are facing or sectioning the block you will smell an odor of xylene
and/or alcohol.

-Beth Poole
HSRL- A GLP Compliant Laboratory
137 South Main Street
Woodstock, VA  22664
fax: (540)459-8217
----- Original Message -----
Sent: Thursday, October 17, 2002 3:58 PM
Subject: underprocessed tissue

> What will an underprocessed piece of tissue that is embedded in a paraffin
> block look like in the center of the tissue, and would you still be able
> section the tissue?? Fixation isn't an issue because this tissue (pig
> was in formalin for several days.
> Bob Meyer
> Northwestern University

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