MAP 2 Antibodies

From:"McMeekin, Bill"

One of our neuropathologists has asked us to add an antibody to our
immunohistochemistry repertoire.  It's for specific microtubule associated
proteins MAP2c,d.  I understand that a recent publication suggests it as a
marker for oligodendroglial differentiation in mixed gliomas/glioblastomas.
We would want to use this on formaldehyde fixed, paraffin embedded (FFPE)
tissue.

The only reference I was given was a possible clone number 'AP18 or C' and I
am not sure if this was an in-house antibody or a commercial one.

The closest I have found so far is a Chemicon antibody to MAP2a,b,c but they
have not tried this on FFPE material.  If anyone is using a commercially
available MAP2c,d I would be grateful for info on the source.

Thanks

Bill McMeekin
Senior Chief Biomedical Scientist
Neuropathology
Newcastle General Hospital
UK





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