Method development for rat tibial bone.

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From:<Kate_E_Rhodes@sbphrd.com> (by way of histonet)
To:histonet@histosearch.com
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Hi Histonetters-We have just begun working on methods development for the
assessment of tibial bone parameters in rats and are wondering if there is any
preferred methods out there.  Any particular decal solution being used to
protect the integrity of the cell structures?  Any consistent way sections can
be cut to examine the epiphyseal growth plate and other bone parameters what
would allow a histomorphometric analysis?  Also, is anyone utilizing a
crown-rump measurement and how do you do it?

Many thanks in advance,
Kate Rhodes
SmithKline Beecham Pharmaceuticals
610-270-7340
FAX 610-270-7202




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