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From: | RUSS ALLISON <Allison@cardiff.ac.uk> (by way of histonet) |
To: | histonet@histosearch.com |
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The history of alcian blue is indeed an interesting one, this not
being the first time it has been going "out of production"
Professor John Scott in the UK spent a considerable portion of his
prfessional life trying to discover the formula of alcian blue. As a
biochemist, he felt it absolutely necessary for his research to know
the formulation. British Drug House BDH (as it then was - now
Merck in the UK and rest of Europe) owned the formula (though
Merck, I believe) and constantly and consistently refused to divulge
the formula. Ironically, it was almost simultaneous with Scott
working it out for himself, by time-consuming experimentation, that
BDH decided to no longer produce the dye and, if I remember
correctly release the formula (perhaps because a patent expired,
but I am not sure of that).
Russ Allison,
Dental School
Cardiff
Wales
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