Then is this host specific antigenic variation due to different
     subspecies of P.carinii infecting their particular favorite flavor of
     host?  Or is there one P.carinii changing its disguise to suit its
     situation (Like the elusive pimpernel)?

     Do the authors of this splendid sounding article offer an explanation?
     My library doesn't carry that journal.  Doesn't carry much of anything
     not relating to engineering, actually.

     Regards

     Simon


______________________________ Reply Separator
_________________________________
Subject: RE: Re[2]: P.carinii
Author:  HistoNet@Pathology.swmed.edu at Internet
Date:    11/12/98 7:14 PM


Host species-specific antigenic variations have been
reported, according to the article I cited.  Pigs
are not dogs are not rats are not people!

-----Original Message-----
From: SMITHS5@pfizer.com [SMTP:SMITHS5@pfizer.com]
Sent: Thursday, November 12, 1998 12:27 PM
To: HistoNet@Pathology.swmed.edu
Subject: Re[2]: P.carinii

     Forgive my stupidity, but won't any antibody to P.carinii label
     P.carinii, whether it be in dog, human, pig, pigeon or muddy puddle?
     Your only problem will be whether tissue processing has altered the
     epitopes on your antigen.

     Regards

     Simon


______________________________ Reply Separator
_________________________________
Subject: RE: P.carinii
Author:  HistoNet@Pathology.swmed.edu at Internet
Date:    11/12/98 1:53 PM


There's a paper in J. Vet. Diag. Investigation where they used the Dako
human antibody on dog tissue and got very nice staining. Sukura, et al
JVDI, 1996 8:124-130 January. Haven't heard about anybody doing immuno on
pigs.

Cindy Farman

-----Original Message-----
From: Greg Dobbin [SMTP:dobbin@Upei.CA]
Sent: Thursday, November 12, 1998 6:32 AM
To: histonet@Pathology.swmed.edu
Subject: P.carinii

I'm looking for several different sources of Pneumocystis carinii
antibody.
Trying to get an antibody to that will cross-react (or  a specific
one if possible??) for P.carinii in swine!

Tried the usual sources but would like to hear all suggestions to see
if I'm missing any. Thanks. Greg
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Greg Dobbin
Pathology Lab
Atlantic Veterinary College, U.P.E.I.
550 Unviversity Ave.
Charlottetown, P.E.I.
C1A 4P3
Phone: (902)566-0744
Fax: (902)566-0851