[Histonet] Upcoming Cold Spring Harbor Symposium

From:"Scott Baldwin"

 To All Histonetters,
     On behalf of the Cold Spring Harbor Symposium,  we would like to let everyone know about the following exciting upcoming symposium. For all that are interested, please note that the third day of the symposium is dedicated to Tissue Analysis and Histopathology applications.

     This is the first announcement of the Inaugural Quantitative Imaging Cytometry Symposium at the Cold Spring Harbor Laboratory, which has been established as part of the Quantitative Imaging Cytometry Regional Center of Excellence activities (http://www.compucyte.com/news-Cold%20Spring%20Release.htm). The symposium will take place at the Cold Spring Harbor, New York campus from January 30 to February 1, 2008.  

The meeting is structured to combine both the theory and practice of QIC, with morning seminars featuring a keynote lecturer and presentations by researchers employing the technology in their work.  Confirmed presentations and speakers include:

·         Time, Biochemistry, and Cell States:  Role of cytometry in systems biology -  James Jacobberger, Professor of Oncology, Case Comprehensive Cancer Center, Cleveland, OH 

·         Laser Scanning cytometry:  Where it fits into modern biomedical analysis - William Telford, NIH/NCI, Bethesda, MD

·         Application of Laser Scanning Cytometry to the Functional Analysis of a Protein Phosphatase in a Mouse Model of Parkinson's Disease - Nicholas Tonks, Director of Shared Resources, Cold Spring Harbor Laboratory Cancer Center, Cold Spring Harbor, NY

·         Quantitative Imaging Cytometry:  How it complements the analytical capabilities of flow cytometry and molecular biology techniques - Zbigniew Darzynkiewicz, Director, Brander Cancer Research Institute, Valhalla, NY 

·         Cell Fate Signaling in Tumor Cells - Shazib Pervaiz, Professor, National University of Singapore

·         Potential Mechanisms for the Generation of Chromosome Aneuploidy in Human Cancer - John M. Lehman, Professor, Brody School of Medicine, East Carolina University, Greenville, NC

·         The Role of Circulating Epithelial Tumor Cells (CETC) in the Metastatic Pathway - Katharina Pachmann, Professor, Department of Experimental Hematology and Oncology, Friedrich Schiller Universität, Jena, Germany

·         Looking at Old Colors with New Lights:  Applying quantitative imaging cytometry to histopathology - William Geddie, Department of Laboratory Medicine and Pathobiology, University of Toronto

·         Quantitative Imaging Cytometry Applications in Pre-Clinical Drug Development -  David Krull, GlaxoSmithKline Safety Assessment, Research Triangle Park, NC

·         Quantitation of Caspase 3 Activation as a Pharmacodynamic Endpoint in Fine Needle Aspirate (FNA) Biopsies - Gloria Juan, Clinical Immunology, Amgen, Thousand Oaks, CA

·         Quantitative Imaging of Biomarkers in Whole Sections and Tissue Microarrays -  Viju Ananthanarayanan, University of Illinois at Chicago, IL


Lectures are followed by small group laboratory sessions providing extensive hands-on practical opportunities for further skill development in applying quantitative imaging cytometry (solid phase laser scanning cytometry) techniques in cell- and tissue-based applications. These sessions will be guided by an expert-level faculty from universities and industry and will focus on the following areas:

1. Practical instruction in designing QIC experiments:  Implementation of high-content cell- and tissue-based applications on the iCys® Imaging Cytometer, quantification of fluorescence and laser light loss, defining assay end-points, dye selection (fluorescent and chromatic), sample preparation for automated analysis, troubleshooting analytical and image performance.

2. Advanced data analysis techniques:  Multiparameter cell cycle; DNA damage; high-content tissue microarray analysis.


3. Individualized application development assistance on requested applications will be offered by experienced staff.  

The Symposium represents an opportunity for users of iGeneration LSC technology to come together to develop advanced skills in the technology, exchange ideas with other researchers and users of LSC technology, and take advantage of customized application development services at no additional cost. Evening poster sessions will provide an opportunity for attendees to further share their work with other researchers.

A full 3-day course fee of $1500 will cover admission to the morning symposia, all afternoon instruction and materials, a peer-reviewed poster session and reception, accommodations for three nights and meals for three days on the Cold Spring Harbor Laboratory campus.  Partial registration packages are also available.

Registration for the meeting is now open at www.imagingcytometrycenter.com, as is the Call for Poster Abstracts.  Registration is limited to 75 people; early registration is therefore recommended.

Scott Baldwin

CompuCyte Corporation


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