Re: [Histonet] Normal Controls for Cerb-B2

From:"Bryan Hewlett"

Tony,

The vast majority of normal epithelial cells express HER2 protein on their 
surface.
However, you would not want to use these as a procedural control,
since the objective is to demonstrate OVER-EXPRESSION of this normal 
protein.
Detection of normal levels of HER2 would invalidate the test.

Bryan

----- Original Message ----- 
From: "Tony Henwood" 
To: 
Sent: Monday, November 20, 2006 12:15 AM
Subject: [Histonet] Normal Controls for Cerb-B2


Hi all,
Apart from Breast and Ovarian tumours (which are rare in pediatric
pathology), does anyone know what normal tissue elements contain this
protein that can be demonstrated using immunohistochemistry?

Regards

Tony Henwood JP, MSc, BAppSc, GradDipSysAnalys, CT(ASC)
Laboratory Manager & Senior Scientist
The Children's Hospital at Westmead,
Locked Bag 4001, Westmead, 2145, AUSTRALIA.
Tel: 612 9845 3306
Fax: 612 9845 3318




**********************************************************************
This email and any files transmitted with it are confidential and intended 
solely for the use of the individual or entity to whom they are addressed. 
If you are not the intended recipient, please delete it and notify the 
sender.

Views expressed in this message and any attachments are those of the 
individual sender, and are not necessarily the views of The Children's 
Hospital at Westmead

This note also confirms that this email message has been
virus scanned and although no computer viruses were detected, the Childrens 
Hospital at Westmead accepts no liability for any consequential damage 
resulting from email containing computer viruses.
**********************************************************************

_______________________________________________
Histonet mailing list
Histonet@lists.utsouthwestern.edu
http://lists.utsouthwestern.edu/mailman/listinfo/histonet



_______________________________________________
Histonet mailing list
Histonet@lists.utsouthwestern.edu
http://lists.utsouthwestern.edu/mailman/listinfo/histonet


<< Previous Message | Next Message >>