[Histonet] Re: How efficient is formalin in killing HIV and Hepatitis?
Teri Johnson, HT(ASCP)QIHC at Stowers Institute for Medical Research in
Kansas City, Missouri asks:
>>Does anybody have published guidelines on how much time it takes for
formalin (10% NBF) to effectively render HIV and Hepatitis non-infective?<<
Obviously it would depend on the thickness of the specimen. HIV would be
inactivated very rapidly. The hepatitis B virus is hardier, but it would not
withstand more than very brief fixation. I think less is known about the hepatitis
C virus, but it's more fragile than B.
Certainly any tissue processing cycle for a properly cut specimen would
suffice. Remember that alcohol is also a very potent viricidal agent.
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