[Histonet] Re: Helicobacter controls
Lee and Peggy Wenk asked about Helicobacter stain controls.
Every lab I've ever worked in just used its positive slides as controls, and
I've found that to be satisfactory. The toluidine blue (e.g. Diff-Quik) stains
don't really need controls. In labs where the histotechs never look at a
slide, it's common to find that the control isn't positive - I sign these out as
"with a suitable control" for regulatory purposes. - The IHC of course requires
Rather rarely these days, you get a gastrectomy specimen that's positive, and
one of these would give you controls for the rest of your life - look for
Helicobacter heilmanii (AKA Gastrospirillum hominis) has the same IHC
reactivity as H. pylori - there's literature about this - it's more common in Japan
than in the USA.
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