Re: Post-fixation of bone marrow specimens

Richard Cartun asks:

>>Is there a minimum time for a B5-fixed bone marrow core biopsy to be 
post-fixed in 10% buffered formalin before decalcification?<<

Assuming you're adding formaldehyde to the B-5 as the formula directs, you 
shouldn't need to post-fix at all. The specimen needs at least an hour in B-5 
before decalcification. 

Clinicians need to understand that if it ain't in the lab by 2 PM (or 
whenever you decide) it doesn't get processed that night.

Bob Richmond
Samurai Pathologist
Knoxville TN

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