Hi, I'm new to this server.  I have a question that may have been discussed numerous times in the past however this problem is new to me.  I have recently had problems with my clearant interferring with immunohistochemistry staining.  CMS changed thier product without letting us know.  I have used a xylene substitute for 16 years and this is the first time there has been a problem.  Has anyone else had a problem with this product (Cittrisolve) and, if so, what did you switch to.   I am not convinced that I need to go back to using xylene. Thanks.