RE: Who was Sertoli?

From:pardi <>

Daer Brett,

Regarding Sertoli, here's a translation (as best as I am able.):

He was born in Sondrio into a noble family and remained there through his
youth. At the age of 18, he moved to Pavia where he studied medecine. In
the 1865 he was awarded a bachelor in medicine and in 1866 he moved to
Vienna where he practiced medecine. Sertoli  enlisted in the military to
serve in war. At the end of the war, he resumed his studies, and animal
research at the Polytechnic of Milan, focusing on problems relative to the
feeding of cattle and milk production. In 1870, at the Veterinary School of
Milan, he accepted the chair of Anatomy and Physiology where he reamined
until to 1904, until the  two subjects were divided into separate
faculties. Sertoli took over the chair of Physiology and his contribution
to the institute in the form of the value of his research continued until
his retirement. The reputation of the Sertoli stems from the discovery in
the seminal epithelium of nutritive (?) or sustaining cells and from the
differentiation between testicular and germinal cells. In particular he
described those cells which today are still identified by his name. These
cells are distinguished from others by the the merging of their bases
towards the apex, allowing sperm to implant themselves for subsequent
trasformation into spermatozoa. The genius that distinguished Sertoli in
the field of the histology, was demonstrated further through his research
into the transport of gases in  blood. In spite of the technical
difficulties caused by having  limited equipment (does this sound like a
histolgy lab or what?),  Sertoli understood the biological significance of
the transport of gases in the blood and the elimination of C02 to the
pulmonary system; he was also one of the first scientists to understand and
to face problems relative to the maintenance of the acid-base equilibrium
in blood. Of special scientific interest were his studies of the analysis
of the contraction of smooth muscles. In fact in 1882, after having to
adapt his own instrumentation for the purpose of his investigation, he
demonstrated that smooth muscles undergo a contraction of long duration and
are sensitive to the thermal stimuli. Sertoli left the scientific scene in
1907 due to illness. He died in 1910.

Paul Ardi
Cell Marque Corp.

At 12:22 PM 11/10/2000 -0500, you wrote:
>Maybe some can translate this.
>> ----------
>> From: 	Gary Radice[]
>> Sent: 	Friday, November 10, 2000 11:48 AM
>> To:
>> Subject: 	Who was Sertoli?
>> Please forgive a non-technique question, but can anyone provide any 
>> biographical info on Sertoli? I assume he (?) was an Italian, but 
>> does anyone know where and when he lived? (I'm lecturing on testis 
>> histology and when I lecture I like to honor the folks who have cell 
>> types named after them).
>> -- 
>> Gary P. Radice
>> Associate Professor of Biology		804 289 8107 (voice)
>> University of Richmond		804 289 8233 (FAX)
>> Richmond VA 23173

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