Glyo-Fixx & GI bx
|From:||ANATECH LTD <email@example.com>|
Tim Webster asked for real-world information on the use of Glyo-Fixx,
especially with GI biopsies.
Glyo-Fixx is a glyoxal-based fixative from Shandon. It is similar in
composition and mode of action to Prefer (Anatech Ltd.), which has
been on the market since 1993. Evaluations of one should suffice for
Strine, Marty, and Bentley published an article on Prefer titled
"Improving biopsies diagnostic cycle-time while preserving optimal
cellular morphology" in the Shandon Lipshaw labLeader 11(2), 1996,
pages 8-9. Eight color photomicrographs of H+E and
immunohistochemistry show the quality possible with glyoxal, even
using extremely short fixation (45-60 minutes). Increasing fixation
time to 2-4 hours would make it even better.
In our own comparative trials with Prefer and zinc formalin, Prefer
won hands down for speed, morphological detail and safety. I am
certain that Glyo-Fixx would prove equally effective for all
Richard W. Dapson, Ph.D.
Battle Creek, MI
Web address: anatechltdusa.com
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