Acid hematin iron stain
Roy Brown at Histology Consultation Services in Oak Harbor, Washington state,
asks:
>>A quick question for anyone.: Does Acid hematin stain with Prussian blue?<<
Acid hematin is a birefringent (lights up with polarizers) pigment, different
from hemosiderin (refractile but not birefringent). Formalin pigment and
malarial pigment are acid hematin. It doesn't color with the prussian blue
reaction like hemosiderin does.
A good geezer reference for this is Lillie 3rd ed.
Pronounced HEE-muh-tin. British spellers write it haematin. Be sure to
distinguish hematin from the hematoxylin oxidation product hematein (British
haematein), pronounced hee-muh-TEE-in.
Bob Richmond
Samurai Pathologist
Knoxville TN
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