Re: Secret (?) IHC chromogen (NovaRED)
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From: | "J. A. Kiernan" <jkiernan@julian.uwo.ca> |
To: | "vector@vectorlabs.com" <vector@vectorlabs.com> |
Reply-To: | |
Date: | Fri, 21 May 1999 11:00:35 -0400 (EDT) |
Content-Type: | TEXT/PLAIN; charset=US-ASCII |
On Thu, 20 May 1999, vector@vectorlabs.com wrote:
> The Vector NovaRED peroxidase
> substrate, similar to our other unique peroxidase and alkaline
> phosphatase substrates (Vector VIP, Vector SG, Vector Red, Vector Blue,
> etc), is a proprietary formulation.
Does this mean it's completely secret, or is the
information disclosed in a patent? If it's truly
secret nobody could use these products in serious
scientific work. What journal would accept results
based on the use of an unknown chemical? What
would a pathologist say in court if a malpractice
case were brought because of a wrong diagnosis?
> As briefly described in our previous
> correspondence, the reaction is similar to that of DAB. However, unlike
> DAB, none of the reagents in the Vector NovaRED substrate are known or
> suspected carcinogens.
Again, are we expected simply to believe this without
knowing the identity of the compound(s)?
> We are unaware of any specific literature
> describing the chemistry of this particular product.
John A. Kiernan,
Department of Anatomy & Cell Biology,
The University of Western Ontario,
LONDON, Canada N6A 5C1
Phone: (519) 679-2111
FAX (Department): (519) 661-3936
E-mail: kiernan@uwo.ca
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