Frank,
I've been using the Accu-edge low profile for years.  I have tried other
brands and have come across the problems with knife lines.  Some brands were
pretty poor.  Cut one block, move the blade, cut another block, move the
blade.  I got fed up with the lesser quality and have stayed with Accu-edge.

Joe Nocito, B.S., HT(ASCP)QIHC
Histology Supervisor
Christus Santa Rosa Hospitals
San Antonio, Texas 
 

> -----Original Message-----
> From:	Frank Walmsley [SMTP:frankw@U.Arizona.EDU]
> Sent:	Wednesday, May 19, 1999 1:03 PM
> To:	histonet@Pathology.swmed.edu
> Subject:	low/high profile blades
> 
> Dear Histonetters,
> 
>      I have been purchasing Accu-Edge high and low profile blades for some
> years now and have had great success with them.  Just recently I started
> to
> try some cheaper blades
> (I will not mention the brand names for fear of defamation) which seemed
> to
> have a striated edge and left tiny lines in the paraffin sections.  I
> couldn't see any problems microscopically with the sections but I'm
> concerned about all these tiny striations I see in the paraffin Vs
> AccuEdge.  Has anyone had any similar experiences with differences in high
> and low profile blade brands???
> 
> 							Thanks,
> 							Frank
> .....................................................................
> : Frank Walmsley, B.S.          Dept. of Cell Biology & Anatomy     :
> : Research Specialist           University of Arizona               :
> : (office:  AHSC 4212)          P.O. Box 245044                     :
> : (voice:  520-626-4415)        Tucson, AZ  85724-5044    USA       :
> : (FAX:  520-626-2097)	        (email:  frankw@u.arizona.edu)
> :
> :...................................................................:
>           http://www.cba.arizona.edu/histology-lab.html