There is such a thing as "amelanotic melanoma"...since this only happens
on a rare occasion, maybe this is it? I would think that the
pathologists would know, though. (We have a professor here who studies
both melanoma and the amelanotic variety, and I did the histo for her
for a while-that's how I know about it.) Just a thought.
Rutgers University, NJ
> You say "they are unable to see the melanocytes". Or is it just the
> melanin granules that are "missing"? Are other cells and structures
> staining normally? Do the granules appear if you use Masson-Fontan or
> some other melanin demonstration technique? Do the problem specimens
> all come from the same source (clinic, surgeon, etc).
> Are you sure you don't have a population of albinos in your region?
> Paul Bradbury
> Kamloops, Canada
> kristen arvidson wrote:
>> Help!! Our pathologists are starting to see a new artifact where they
>> are unable to see the melanocytes (we are all derm). It only happens
>> on a rare occasion. We checked the PH of the water on the stainer
>> and it seemed fine. We can't think of anything else? Help!
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