They are not manufactured with a "standard angle" because according with the RESISTANCE of the material to cut, due to the intrinsic characteristics of the tissue (more or less "solid" or "resistant") you should experiment with the "ideal angle" for that particular block.
In the general pathology practice being all human tissues and most of them infiltrated with the same melting point paraffin, they "become" of a "quasi standard" resistance level that can allow a single angle for all microtomes. Under those circumstances it is better to have all microtomes working at the same angle and allowing any HT to recut a block initially cut by any one of the other HTs in the lab.
"Hofecker, Jennifer L" wrote:
Histonet mailing list