Addendum to previous: we process most mouse tissue on a 9 hour cycle.
Makes quite a difference- very few crispy critters.
Bernice Frederick HTL (ASCP)
Pathology Core Facility
710 N Fairbanks Court
[mailto:email@example.com] On Behalf Of Gayle
Sent: Monday, May 14, 2007 1:30 PM
To: Linda Jenkins; Histonet@lists.utsouthwestern.edu
Subject: Re: [Histonet] RE:Switching from hospital histo to Research
Dear Linda and Carol,
Another thing - develop an invaluable network of research histotechs to
help you as you go along. Histonet is one place to find these people,
in the end, you will spend a lot of time with them in very lengthy
conversations. Attending NSH workshops and participating in their
committees has been a huge help to our laboratory, right down on how to
up GLP, and just about any other methodology -
As for Linda, she is one of my invaluable contacts - sharing ideas,
literature, the lost method, problem solving with individuals like her
only boosts your knowledge but you also become good friends along the
and maybe someday co-present workshops on various reserach related
as we have done.
Enjoy your research experience - and remember to avoid those "crispy
Research Histopathology Supervisor
Veterinary Molecular Biology
Montana State University - Bozeman
PO Box 173610
Bozeman MT 59717-3610
At 12:48 PM 5/14/2007, you wrote:
> You stated:
> " I'm contemplating making a switch from a routine hospital histology
> department to supervising a pharmaceutical research histology dept.
> working with mostly rodent tissue. Any opinions, suggestions, or
> resources anyone would like to contribute would be greatly
> appreciated. It seems like a much less stress level than a hospital
> at times,..... so what am I missing or not thinking about as far as
> "problems" in this type of histology?"
> Well, I made the switch 18 years ago and the thoughts of going
> back to clinical have never entered my mind. What's not to like?
> pay, better benefits, MUCH less stress, no more working holidays or
> weekends unless I choose to do so. I think the primary ingredient to
> successful transfer is that you must be self motivated and capable of
> independent work. In clinical your days are fairly well defined (e.g.
> embed, section, stain, etc.). In research, you just never know what
> day will bring. If you like orderly, routine days then you might want
> stay in clinical. I brought human protocols to my research lab and
> all had to be severely modified. Rodent tissue is so lean you must
> modify processing protocols or you will end up with (as Gayle Callis
> says) "crispy critters". You will be asked to perform stains you have
> only read about and they will probably need to be modified on top of
> that. The only thing I really miss is being able to consult with a
> pathologist and histology colleagues when I encounter problems. Part
> that problem was solved by joining NSH's VIR & Hard Tissue committees
> where I have bunches of "bonehead buddies" doing the stuff I am. I
> haven't found a research pathologist - much to my chagrin.
> I thought I was happy in clinical histology until I entered
> world of research. Now, I know true happiness!
> Hope this helps,
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