[Histonet] Breast Marker Question


What are the top two best markers for labeling the basement membrane components and myoepithelial cells of breast tissue (or maybe not the myoepithelial cells)?  We're looking for antibodies that would assist in differentiating between invasive and non-invasive breast carcinomas. One of our pathologists wants Laminin and Collagen Type IV, but the article I found was real old.  Are these two antibodies possibilities or are labs using other more sensitive and/or specific markers.

Laura Bliven
Histology Lab/IHC
Marshfield Laboratories
1000 N. Oak Ave.
Marshfield, WI 54449

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