RE: [Histonet] freezing of specimens in surgery center

From:"Mitchell Jean A."

"Storage: Keep away from sources of ignition. Keep container closed when
not in use. Store in a cool, dry, well-ventilated area away from
incompatible substances. Refrigeration has been recommended."

The above is directly from a well known company's current MSDS on
storage of isopentane.  And I know sorting through MSDS's attempting to
get a straight answer on on chemical health issues, shelf life, storage
can be extremely frustrating.

It may be an ignorant question to ask but; Is it not possibly safer to
store isopentane (2-Methylbutane) at room temperature vs refrigeration? 

Jean Mitchell, BS, HT (ASCP)
University of Wisconsin Hospital & Clinics
Neuromuscular Laboratory
Madison, WI

-----Original Message-----
[] On Behalf Of
Elizabeth Chlipala
Sent: Tuesday, May 24, 2005 11:59 AM
Subject: [Histonet] freezing of specimens in surgery center

Hello Histonetters
I have a unique question.  We are currently starting to set up procedure
for collecting samples from a clinical trial.  The clinical trial
involves taking multiple synovial biopsies at a surgery center.  Since
portions of the samples need to be processed for frozen sections we
wanted to be able to freeze the specimens at the surgery center via
isopentane cooled liquid nitrogen.  We really do not want to have to
transport the multiple specimens back to the main lab prior to freezing
due to the time involved it would probably be 1-2 hours post biopsy
before we could freeze the samples.  The surgery center is questioning
the flammability of the isopentane.  Has anyone encountered anything
like this?  Any suggestions would be helpful.  Thanks in advance.
Elizabeth A. Chlipala, BS, HTL(ASCP)QIHC Manager Premier Laboratory, LLC
P.O. Box 18592 Boulder, Colorado 80308
Office: (303) 735-5001
Fax: (303) 735-3540
Ship to Address:
Premier Laboratory
University of Colorado
MCDB, Room A3B40
Boulder, Colorado 80309
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