Re: Xylene substitutes


I have been using Thermo Shandon's Xylene Substitute (HistoSolve) for approximately 10 years.  We use it in the processor and on the stainging lines of our routine stains and our IHC.  We have had no problems or complaints in using it.  If you are looking for a substitute I would highly recommend it.  It is not greasy nor is it citrus smelling.
Hope this helps.
Dawn Schneider, HT(ASCP)
Howard Young Medical Center
Woodruff, WI
-----Original Message-----
From: Valerie Hannen <>
To: histonet <>
Date: Sunday, May 26, 2002 9:33 PM
Subject: Xylene substitutes

Does anyone know of any "great" xylene substitutes?
We need one that is good for all aspects of processing.
Processing, staining, coverslipping. It can't have a terrible
citrus smell (tried one like that and it was horrible). Must
be ok to use with IHC. Our safety officer wants us to try
"safer" clearing agents.
Thanks for any input you can give me.
Valerie Hannen,MLT(ASCP),HTL
Parrish Medical Center
Titusville, Florida 32796

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