Dear Richard,

This product is a preservative of RNA, not a tissue fixative.
Tissue still needs to be fixed, unless it is fresh eg cultured cells.
Check this link
http://www.ambion.com/techlib/tn/72/725.html and notice that the tumour
tissue was fixed in acetic alcohol. Tissue frozen in RNAlater may prove
difficult to cryosection.
I found RNAlater is not useful for preserving RNA during IHC, for subsequent
microdissection and extraction.

hooroo,richard
-----Original Message-----
From: Richard Edwards <REE3@leicester.ac.uk>
To: histonet@pathology.swmed.edu <>
Date: Friday, 18 May 2001 18:41
Subject: RNAlater


>
>
>     Anyone  out  there  had  any  experiance  of  using  RNAlater  as  a
>fixative??????????????
>                                     Thanks
>                                           Richard  Edwards
>                                                         MRC TOXICOLOGY
UNIT
>                                                                LEICESTER
>
U.K.................
>
>