Re: polyoma virus

From:burch007@mc.duke.edu


Carmen:

Here is the information you need for the BK Polyomavirus:

BK Polyomavirus
Chemicon's monoclonal antibody to BK polyomavirus,
large T antigen, catalog # MAB8505, used at a dilution of 1:16,000 in
conjunction with DAKO's mouse Envision Plus detection system. Consistent
IHC staining is accomplished with the use of trypsin as the proteolytic
enzyme of choice.

BK virus infects a variety of urinary tract epithelia of immunocompromised
patients and with increasing frequency renal transplant recipients. This
antibody does not react with the JC polyomavirus, however, JC polyomavirus
will react with BK polyomavirus.

DIAGNOSIS AND MANAGEMENT OF BK POLYOMAVIRUS INFECTIONS IN RENAL TRANSPLANT
RECIPIENTS. DN Howell, SR Smith, DW Butterly, PS Klassen, HR Krigman, JL
Burchette, SE Miller. Transplantation, Vol. 68, No. 9, pages 1279-1288,
November 1999.

E-mail if you have any questions or need additional help.

Sincerest regards,

Jim Burchette
Duke University Health System
Dept. of Pathology
Immunopathology Lab
Durham, NC
919-681-3973




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