Manganese staining
From: | Patsy.Ruegg@UCHSC.edu |
Mn is usually measured indirectly by differing combinations of urine,
blood serum, hair samples, an MRI, or monitoring the activity of
manganese-activated enzymes and metalloenzymes etc. None of these
methods
are perfect biomarkers. John says if one is a good chemist, you might
be
able to made up a stain of permanganate like a Potassium permangate when
applied to a slide may glow purple( this is a guess). I also looked
for
stains in literature but did not find any, when I was looking at
toxicity.
Manganese often appears not to stay in tissue, rather leaves a trail of
damage which progresses after the withdrawal of exposure.
On Thu, 3 May 2001 Patsy.Ruegg@UCHSC.edu wrote:
> Hi Kathy,
> Was wondering if John could help with this inquiry?
> Patsy
>
> -----Original Message-----
> From: Histo-Scientific Research Laboratories
[mailto:histosci@shentel.net]
> <mailto:[mailto:histosci@shentel.net]>
> Sent: Thursday, May 03, 2001 6:08 AM
> To: Linda McGraf
> Subject: Manganese staining
>
> Dear Histonetters,
>
> Has anyone ever heard of staining for localization of manganese in
animal
> tissue? We have looked through our staining books and have come up
with
> nothing. If anyone has ever heard of such a procedure, please share
any
> info you may have.
> Thank you,
>
> Beth Poole
> HSRL
> beth@hsrl.org <mailto:beth@hsrl.org>
> (540)459-8211
> fax: (540)459-8217
> www.hsrl.org <http://www.hsrl.org>
> 137 South Main Street
> Woodstock, VA 22664
>
>
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