Eric et al,
Do you know where I could find antibodies to bone morphogenic protein
receptors:
BMPR-1A  also known as ALK3, BRK1 
BMPR-1B also known as ALK6, BRKII, RPK-I
BMPII receptor also known as ACTR-II
Another BMP receptor known as ACTR-I 
Patsy Ruegg

		-----Original Message-----
		From:	Kellar, Eric [mailto:kellarec@MSX.UPMC.EDU]
		Sent:	Tuesday, March 23, 1999 12:03 PM
		To:	'Histonet'; 'Drew Sally A.'
		Subject:	RE: CR43/3? or CR3/43? Or?

		Sally,

		The Microglia home page is a nice source - 

		http://www.lrz-muenchen.de/~u792201/www/microglia.html


		                 CCR3 and CCR5 are Co-Receptors for HIV-1
		                 Infection of Microglia

		                 He, Jianglin; Chen, Youzhi; Farzan,
Michael; et al.

		                 The three chemokine co-receptors known to
be involved in
		HIV-1
		                 infection--CCR5, CXCR4, and CCR3--are found
in various
		types of cells and
		                 tissues. Resistance to HIV-1 infection has
been linked to
		defective CCR5
		                 alleles, suggesting that CCR5 plays an
important role in
		HIV-replication in the
		                 body. In the central nervous system (CNS),
HIV-1 targets
		brain cells known
		                 as microglia and causes AIDS-related
dementia. Researchers
		now report that
		                 these target cells express both CCR3 and
CCR5. The
		researchers found that
		                 the CCR3 ligand, eotaxin, and an anti-CCR3
antibody
		inhibited HIV-1
		                 infection in the brain cells, as did a CCR5
ligand. The
		authors suggest that both
		                 co-receptors promote HIV-1 infection of the
CNS and that
		the identification of
		                 CCR3's role in the infection of microglia
may lead to new
		treatments for
		                 AIDS-related dementia. 

		 The CDC National Center for HIV, STD, and TB Prevention
makes this
		information available as a public service
		 only. Providing this information does not constitute
endorsement by the
		CDC. Reproduction of this text is
		 encouraged; however, copies may not be sold, and the CDC
National AIDS
		Clearinghouse should be cited as
		 the source. Copyright 1996, Information, Inc., Bethesda,
MD.

		 Eric Kellar
		 Histology/Immunohistochemistry
		 University of Pittsburgh Medical Center


		> ----------
		> From: 	Drew Sally A.[SMTP:sa.drew@hosp.wisc.edu]
		> Sent: 	Monday, March 22, 1999 4:43 PM
		> To: 	'Histonet'
		> Subject: 	CR43/3? or CR3/43? Or?
		> 
		> Is anyone familiar with an antibody to microglia?  I've
been given the
		> terms CR43/3 or CR3/43...would these be clones of
something named
		> something
		> else? I would appreciate any help with this, I don't even
have any journal
		> articles to refer to....!  
		> 
		> Sally Ann Drew, MT(ASCP)
		> U.of Wis. Hosp. & Clinics
		> IHC/ISH  Clin./Research Lab
		> 600 Highland Ave. A4/204-2472
		> Madison, WI 53792-2472
		> Tel. (608)265-6596
		> Fax:(608)263-1568
		> 
		>