Have you tryed  PenFix from Richard Allan Scientific for those kind of
tissues, it is also a mixture, and works Great.

"Goodwin, Diana" wrote:
> 
> Dear Tami,
> 
> We have found that pre-fixing fatty tissue, such as breast, in some kind
> of alcohol-formalin mixture has helped immensely.  We have also
> implemented an alcohol-formalin station on our tissue processor ( after
> 10% NBF and before the first alcohol).  We are mixing our own, using a
> 10% solution of 37-40% formaldehyde in 80% ethanol.
> 
> Hope this helps!
> 
> Diana Goodwin, HT
> Trenton,  NJ
> 
> > ----------
> > From:         Tami Lee[SMTP:Tami.Lee@css.unc.edu]
> > Sent:         Monday, March 08, 1999 8:50 AM
> > To:   HistoNet@pathology.swmed.edu
> > Subject:      troublesome tissues
> >
> > Hi everyone,
> >       I am trying to fix, process, and section breast and uterine
> > tissue.
> > Although the uterus was fixed
> > in 10% NBF for several days, it still appeared to have areas that were
> > poorly
> > fixed.  The processing
> > schedules that I have been using are 12 hours long, and do not seem to
> > be
> > effective, especially
> > on the breast tissue.  Does anyone have any advice they wouldn't mind
> > sharing?
> > I have not been able
> > to find anything in our laboratory's textbooks.
> > Thanks in advance,
> > Tami Lee
> >