Patsy,


R&D Systems
614 McKinley Place N
Minneapolis, MN 55413
Tel: 1-800-343-7475
        (612) 379-2956
Fax: (612) 379-6580

ACTR-1 & 2
Research Diagnostics Inc 
Pleasant Hill Road 
Flanders NJ 07836 
phone (800) 631-9384 
      or  (973) 584-7093 
ax     (973) 584-0210 
EMAIL:ResearchD@aol.com

Eric Kellar
Histology/Immunohistochemistry
University of Pittsburgh Medical Center

	----------
	From:  Patsy.Ruegg@UCHSC.edu [SMTP:Patsy.Ruegg@UCHSC.edu]
	Sent:  Wednesday, March 24, 1999 4:50 PM
	To:  kellarec@MSX.UPMC.EDU
	Cc:  histonet@pathology.swmed.edu
	Subject:  more antibody searches

	Eric et al,
	Do you know where I could find antibodies to bone morphogenic
protein
	receptors:
	BMPR-1A  also known as ALK3, BRK1 
	BMPR-1B also known as ALK6, BRKII, RPK-I
	BMPII receptor also known as ACTR-II
	Another BMP receptor known as ACTR-I 
	Patsy Ruegg

			-----Original Message-----
			From:	Kellar, Eric [mailto:kellarec@MSX.UPMC.EDU]
			Sent:	Tuesday, March 23, 1999 12:03 PM
			To:	'Histonet'; 'Drew Sally A.'
			Subject:	RE: CR43/3? or CR3/43? Or?

			Sally,

			The Microglia home page is a nice source - 

	
http://www.lrz-muenchen.de/~u792201/www/microglia.html


			                 CCR3 and CCR5 are Co-Receptors for
HIV-1
			                 Infection of Microglia

			                 He, Jianglin; Chen, Youzhi; Farzan,
	Michael; et al.

			                 The three chemokine co-receptors
known to
	be involved in
			HIV-1
			                 infection--CCR5, CXCR4, and
CCR3--are found
	in various
			types of cells and
			                 tissues. Resistance to HIV-1
infection has
	been linked to
			defective CCR5
			                 alleles, suggesting that CCR5 plays
an
	important role in
			HIV-replication in the
			                 body. In the central nervous system
(CNS),
	HIV-1 targets
			brain cells known
			                 as microglia and causes
AIDS-related
	dementia. Researchers
			now report that
			                 these target cells express both
CCR3 and
	CCR5. The
			researchers found that
			                 the CCR3 ligand, eotaxin, and an
anti-CCR3
	antibody
			inhibited HIV-1
			                 infection in the brain cells, as
did a CCR5
	ligand. The
			authors suggest that both
			                 co-receptors promote HIV-1
infection of the
	CNS and that
			the identification of
			                 CCR3's role in the infection of
microglia
	may lead to new
			treatments for
			                 AIDS-related dementia. 

			 The CDC National Center for HIV, STD, and TB
Prevention
	makes this
			information available as a public service
			 only. Providing this information does not
constitute
	endorsement by the
			CDC. Reproduction of this text is
			 encouraged; however, copies may not be sold, and
the CDC
	National AIDS
			Clearinghouse should be cited as
			 the source. Copyright 1996, Information, Inc.,
Bethesda,
	MD.

			 Eric Kellar
			 Histology/Immunohistochemistry
			 University of Pittsburgh Medical Center


			> ----------
			> From: 	Drew Sally
A.[SMTP:sa.drew@hosp.wisc.edu]
			> Sent: 	Monday, March 22, 1999 4:43 PM
			> To: 	'Histonet'
			> Subject: 	CR43/3? or CR3/43? Or?
			> 
			> Is anyone familiar with an antibody to microglia?
I've
	been given the
			> terms CR43/3 or CR3/43...would these be clones of
	something named
			> something
			> else? I would appreciate any help with this, I
don't even
	have any journal
			> articles to refer to....!  
			> 
			> Sally Ann Drew, MT(ASCP)
			> U.of Wis. Hosp. & Clinics
			> IHC/ISH  Clin./Research Lab
			> 600 Highland Ave. A4/204-2472
			> Madison, WI 53792-2472
			> Tel. (608)265-6596
			> Fax:(608)263-1568
			> 
			>