Re: p53

<< Previous Message | Next Message >> (Ann Samways),
Date:Mon, 08 Mar 1999 09:43:53 -0500 (Eastern Standard Time)


Several years ago we published an artical in Carcinogenesis on the
demonstration of p53 in mice using a polycolnal antibody from Signet Lab.'s. 
This antibody also worked well in rats (unpublished) but we did not try it on
hamsters.  The reff. is:

Hegi, M.E., P. Soderkvist, J.F. Foley, R. Schoonhoven, J.A. Swenberg, R.R.
Maronpot, M.W. Anderson and R.W. Wiseman.  Characterization of p53 mutations
methylene chloride-induced lung tumors from B6C3F1 mice. Carcinogenesis
15:803-810 (1993).

-- Begin original message --
> Hi,
> Has anyone done Immunohistochemistry using Paraffin sections from Rat and
> Hamster with p53.We have worked alot with D07 and 1801 but these are -ve
> with Rat and Mice.
> If so, please supply with name of Protein and Company to buy through.
> Thanks in advance.
> Ann
> Ann Samways,
> Histology Unit,
> Dept of Stomatology,
> School of Dentistry,
> P.O. Box 647,
> Dunedin.
> New Zealand
> Phone (O3) 4797079
> Fax   (03) 4790673
> Email--
-- End original message --

best regards,
Robert Schoonhoven
Laboratory of Molecular Carcinogenesis and Mutagenesis
Dept. of Environmental Sciences and Engineering
University of North Carolina
Chapel Hill, NC 27599
office 919-966-6343
   Lab 919-966-6140
   Fax 919-966-6123 

**Suppose you were an idiot... And suppose you were a member of Congress ...
But I repeat myself.-Mark Twain**

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